Glenna met her husband Ed in southern Oregon when he returned from service with the U.S. Army in Vietnam. They were married in 1968. In 1970, when their oldest daughter Carmen was just six weeks old, they moved to Montana, where Glenna attended, and Ed graduated from Montana Institute of the Bible. They joined InterAct Ministries (then Arctic Missions) in 1977 and began a church-planting ministry among the Chilcotin Indians of British Columbia. After four years, they moved to Williams Lake, where they helped establish the Williams Lake Native Bible Church. They relocated to Alberta in 1986 to minister as InterAct’s Canadian mobilizers. In 2001 the Houstons joined co-workers in Kamloops, BC, in their church plant among Shuswap First Nations people. In 2003 Ed and Glenna took the reins of Native Bible Centre (NBC), a distance-learning Bible school. In 2011, they moved to Wardner, BC, to continue directing NBC and the production of “TRIBE” (Training Resources for Indigenous Bible Education) materials. In 2019, Ed went home to be with the Lord, and two years later, Glenna moved to Olds, AB, to be near family. She retired in 2024.